PC2002 - Molecular Basis of Therapeutics 3
| Credit points: | 03 |
| Year: | 2018 |
| Student Contribution Band: | Band 2 |
| Administered by: | College of Science and Engineering |
Available to students enrolled in the Bachelor of Pharmacy.
This subject builds upon the fundamental concepts of pharmacology and medicinal chemistry introduced in the first year of the Pharmacy program. It deals with the concepts of pharmacokinetics, including the mechanisms of drug metabolism and excretion. The subject also introduces the basic principles of toxicology. The importance of chemical analysis in relation to drug development, forensic science, drug testing and clinical diagnosis is examined. Specific topics to be covered include instrumental methods of analysis and structure determination (particularly NMR, chromatographic separation techniques (HPLC and GLC, thermal analysis methods (DSC and TGA) and Vibrational Spectroscopic techniques (FTIR and Raman spectroscopy). Approaches to the development of new pharmaceutical agents, including pharmacognosy, rational drug design and high-throughput screening are also introduced.
Learning Outcomes
- identify current approaches to the development of new pharmaceutical agents, including mechanisms of drug metabolism and excretion;
- describe and apply spectroscopic techniques used in the quality control of pharmaceuticals, in drug testing & development;
- explain polymorphism and the analytical techniques used to differentiate them;
- describe modern purification techniques in pharmaceutical chemistry;
- employ basic synthetic techniques to synthesise model pharmaceuticals and undertake their analysis in a practical setting.
| Prerequisites: | CH1001 and PC1005 |
| Inadmissible Subject Combinations: | PP3150, CH2043, CH3403 |
Availabilities | |
| Townsville, Internal, Study Period 1 | |
| Census Date 22-Mar-2018 | |
| Coordinator: | Dr Mark Robertson |
| Lecturers: | Assoc. Professor Michael Oelgemoeller, Professor Peter Junk. |
| Contact hours: |
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| Assessment: | end of semester exam (70%); laboratory performance and reports (30%). |
| Special Assessment Requirements: | To pass this subject you must: get an overall score of 50% or greater; score at least 45% in both the individual components (exam and practicals); complete mandatory induction and practical sessions. |
Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.