CH2010 - Biological Chemistry

Credit points:	03
Year:	2017
Student Contribution Band:	Band 2
Administered by:	College of Science and Engineering

None

<b>General Chemistry revision</b> Acid/base and organic functional group chemistry. <b>Natural Product Chemistry</b> Extraction, chromatography, analysis, spectroscopy; terpenes, steroids, alkaloids, lignins. <b>Bio-organic Chemistry</b> Structure and function of carbohydrates, proteins and DNA; <b>Disperse systems</b> macromolecular colloids, emulsions. <b>Bio-inorganic Chemistry</b> Coordination complexes. Hemoglobin, Chlorophyll metalloenzymes. Photosynthesis : Rubisco and the C3 photosynthetic pathway. <b>Enzymatic Chemistry</b> The function of enzymes, inhibitors, cofactors, coenzymes and vitamins. <b>Lipids and Membranes</b> Fatty acids, complex lipids, lipid proteins, steroids, fluid mosaic membrane. Passive/active transport. <b>Bioenergetics</b> Catabolic and anabolic reactions. The metabolic role of ATP. Fatty acid synthesis. Glucogenesis. Glycolysis and the citric acid cycle. <b>Electron Transport</b> Oxidative phosphorylation. Shuttles. <b>DNA Processes</b> Replication, transcription and translation. Recombinant DNA and PCR. DNA microarrays. Oncogenes, Cancer drugs. Gene regulation. Signal transduction.

Learning Outcomes

• have developed an understanding of molecular processes involved in natural product chemistry and biochemistry;
• have surveyed the use of molecular techniques appropriate to working with natural products and biochemicals, with practical experience in the use of many of these methods;
• been provided with a general theoretical framework on the aspects of chemistry/biochemistry that are important in the biological sciences;
• be able to express scientific ideas using written communication skills;
• be able to interpret and analyze data, generated from experimental or theoretical problems.

Prerequisites:	(CH1011 OR CH1001)
Inadmissible Subject Combinations:	BM1000 CH1010

Availabilities
Cairns, Internal, Study Period 1
Census Date 23-Mar-2017
Coord/Lect:	Assoc. Professor Michael Liddell.
Contact hours:	35 hours lectures 18 hours practicals 10 hours - Guided learning session
Assessment:	end of semester exam (55%); other exams (18%); essays (10%); marks for practical excercises (17%).
Special Assessment Requirements:	Practical component: students will fail the course if they miss 2 or more practicals without a valid reason (generally medical certificates will be required).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.