CH2010 - Biological Chemistry

Credit points:	03
Year:	2012
Student Contribution Band:	Band 4
Administered by:	School of Pharmacy & Molecular Sciences

None

<b>General Chemistry revision</b> Acid/base and organic functional group chemistry. <b>Natural Product Chemistry</b> Extraction, chromatography, analysis, spectroscopy; terpenes, steroids, alkaloids, lignins. <b>Bio-organic Chemistry</b> Structure and function of carbohydrates, proteins and DNA; <b>Disperse systems</b> macromolecular colloids, emulsions. <b>Bio-inorganic Chemistry</b> Coordination complexes. Hemoglobin, Chlorophyll metalloenzymes. Photosynthesis : Rubisco and the C3 photosynthetic pathway. <b>Enzymatic Chemistry</b> The function of enzymes, inhibitors, cofactors, coenzymes and vitamins. <b>Lipids and Membranes</b> Fatty acids, complex lipids, lipid proteins, steroids, fluid mosaic membrane. Passive/active transport. <b>Bioenergetics</b> Catabolic and anabolic reactions. The metabolic role of ATP. Fatty acid synthesis. Glucogenesis. Glycolysis and the citric acid cycle. <b>Electron Transport</b> Oxidative phosphorylation. Shuttles. <b>DNA Processes</b> Replication, transcription and translation. Recombinant DNA and PCR. DNA microarrays. Oncogenes, Cancer drugs. Gene regulation. Signal transduction.

Learning Outcomes

• develop an understanding of molecular processes involved in natural product chemistry and biochemistry;
• survey of molecular techniques appropriate to working with natural products and biochemicals, with practical experience in the use of these methods;
• to provide a general framework on the aspects of chemistry/ biochemistry that are important in the biological sciences.

Graduate Qualities

• The ability to think critically, to analyse and evaluate claims, evidence and arguments;
• The ability to adapt knowledge to new situations;
• The ability to lead, manage and contribute effectively to teams;
• The ability to speak and write logically, clearly and creatively;
• The acquisition of coherent and disciplined sets of skills, knowledge, values and professional ethics from at least one discipline area;
• The ability to reflect on and evaluate learning, and to learn independently in a self directed manner.

Prerequisites:	(CH1011 AND CH1012) OR (CH1001 AND CH1002)
Inadmissible Subject Combinations:	BM1000 CH1010

Availabilities
Cairns, Internal, Study Period 1
Census Date 22-Mar-2012
Coord/Lect:	Assoc. Professor Michael Liddell.
Contact hours:	36 hours lectures 10 hours tutorials 30 hours practicals 10 hours - LearnJCU modules.
Assessment:	end of semester exam (35% - 55%); quizzes or tests (25% - 45%); essays (5% - 15%); marks for practical exercises (15% - 25%).
Special Assessment Requirements:	Practical component: students will fail the course if they miss 3 or more practicals without a valid reason (generally medical certificates will be required).

Note: Minor variations might occur due to the continuous Subject quality improvement process, and in case of minor variation(s) in assessment details, the Subject Outline represents the latest official information.