CH3032:03
Organic Chemistry
| Townsville | HECS Band 2 |
32 hours lectures, 4 hours tutorials, 36 hours practicals. Semester 2.
Staff: Assoc. Professor G Meehan, Assoc. Professor B Bowden.
A broad study of contemporary organic chemistry comprising: Structure analysis: Application of instrumental methods to the determination of the structure and composition of organic compounds. Major emphasis will be placed on 1H and 13C nmr techniques (both 1D and 2D) and on the interpretation of mass spectral fragmentation. Reaction mechanisms: An examination of the experimental basis for the proposal, testing and refinement of the mechanisms of organic reactions. Organic synthesis: Selective methods of carbon-carbon bond formation and functional group manipulation; selectivity of reagents, stereoselectivity.
The disconnection approach to designing organic syntheses.
Bioorganic chemistry: Review of the major classes of natural products from living systems based on their biosynthetic origins. Selected enzyme mechanisms.
Learning Objectives:
- be familiar with the range of instrumental techniques used for the structure determination of organic compounds and be able to apply these to the solution of unknown structures including relatively complex examples;
- understand the experimental basis for the proposal, testing and refinement of reaction mechanisms;
- have a broad knowledge and understanding of methodology employed in contemporary organic synthesis and synthesis design;
- be familiar with the major classes of natural products from living systems and understand their modes of biosynthesis;
- be familiar with, and competent in the application of, advanced laboratory techniques in organic chemistry.
Assessment by a three-hour examination (70%); in-course assessment of practical work and reports (30%).