CH3100:03
Molecular Basis of Therapeutics 4
Townsville
Prerequisites: BC2014 BC2025 PC2001 PC2002
30 lectures, 6 tutorials, 36 hours practicals/problem sessions. First semester.
Available to students who are enrolled in the BPharm and have successfully completed all prerequisite level 2 subjects. It will also be made available to other science-based students who have appropriate prerequisite subjects as determined by the Head of the discipline of Chemistry.
Staff: Assoc. Professor G Meehan, Assoc. Professor B Bowden, other lecturers with appropriate expertise.
This subject will examine the medicinal chemistry relevant to the process of drug discovery and development as practised in the modern pharmaceutical industry. Building on the material covered in PC2001 and PC2002, it will develop in students a knowledge of the research tools which are applied to this process — including high throughput screening, computational chemistry and molecular modelling, QSAR, combinatorial synthesis techniques and the application of genomics. The specific application of these tools to drug classes of clinical significance will be illustrated by a case-study approach.
Learning Objectives:
- an appreciation of the interdisciplinary nature of the drug discovery and development process;
- knowledge of the range of research tools available for this process;
- experience of the application of these tools to specific drug classes of clinical significance.
Assessment by a three-hour examination (70%); practicals and other on-course assessment (30%).