SCHOOL OF PHARMACY AND MOLECULAR SCIENCES
Biochemistry and Molecular Biology
Molecular biology, evolution and biochemistry
of plant carbonic anhydrases;
Regulation of C3 and C4 photosynthesis;
Biotechnology of crop plants;
Development of novel herbicides;
Molecular biology of dengue virus replication;
Bacterial signal transduction;
Protein-protein interactions;
Biochemical investigation of symbiosis in corals and clams;
Dinoflagellate Rubisco and CO2 fixation;
Evolution of developmental mechanisms;
Molecular developmental biology of animals;
Coral evolutionary genetics;
Molecular genetics of light-harvesting in dinoflagellates;
Molecular evolution;
Regulation of gene expression in animals and plants;
Biological function of protein protease inhibitors;
Molecular genetics of cell division and DNA
repair.
Chemistry
Synthesis of biologically and
pharmacologically active molecules; medicinal chemistry;
Host-guest and supramolecular chemistry; molecular
recognition; molecular devices;
Spectroscopic, stereochemical and reactivity
studies of polymetallic molecular assemblies and their application
to photochemical molecular devices;
Molecular structure, molecular assemblies and
molecular interactions using x-ray diffraction, NMR and ESR;
Theoretical and computational chemistry;
Computer modelling applied to atmospheric chemistry
and to transition metal clusters;
Novel active compounds from marine organisms
and terrestrial plants;
Environmental geochemistry of metals in natural
water systems;
Role of organic molecules in the ecology of
marine organisms;
Marine pollution studies;
Chemical and physical speciation of metals
in natural waters;
Atmospheric chemistry – trace gas
measurements;
Development of, and mechanistic studies on,
transition metal (platinum) complexes as anticancer agents;
Investigations into magnetic exchange interactions of multinuclear metal
complexes.
Pharmacy
Population pharmacokinetics of
methotrexate in paediatric oncology patients;
The role of evoked otoacoustic emission testing
in patients receiving ototoxic therapy;
The role of mMode echocardiography in the monitoring
of cardiotoxicity in patients receiving anthracycline therapy;
Population pharmacokinetics of perhexiline;
Population pharmacokinetics of magnesium sulphate;
Photo- and thermal stability studies on selected
drug molecules;
Cyclodextrin chemistry;
Drug formulation studies for the enhancement of the thermal
and photostability of selected drug molecules;
In-use stability studies in rural and remote placements.
Intestinal metabolism and drug transport;
Medicinal chemistry, stability/stabilisation and
solubilisation of oligopeptides;
Molecular modelling and drug screening.
Development of first-aid pharmacological interventions for
neurotrauma;
Characterisation of the role of neuropeptides in neurogenic inflammation
and the development of pharmacological interventions;
Identification and characterisation of novel peptidergic
receptor subtypes
and the development of novel therapeutic interventions;
Examination of the hormonal regulation of neurotransmitter
receptor number and function;
Development of high-throughput screening assays for the identification of
potential lead compounds for pharmacological
development.